Isoxazolines and Seizures: A Vet's Guide to Flea & Tick Products

For most pets in paralysis tick areas (e.g. the East Coast of Australia)

Using an isoxazoline product is strongly recommended. Most Australian vets agree that the significant benefit of preventing potentially fatal tick paralysis far outweighs the very low risk of adverse effects.

For pets with a history of seizures living in tick areas

You must consult your veterinarian. These pets may have a greater risk of side effects. Your vet can discuss alternative products, such as Advantix (for dogs only) or a Seresto collar (for dogs and cats). While these alternatives are not in the isoxazoline class, they are generally considered less effective. However, using them is significantly better than having no tick protection at all.

For pets living in non-paralysis tick areas

You have more flexibility. You can comfortably choose an isoxazoline or one of the other products mentioned. It's still important to have tick protection, as other species like the brown dog tick and the bush tick can still cause significant irritation and spread disease.

A special note for some areas (e.g. Northern Territory and Western Australia)

Due to the high risk of a different tick-borne disease called Ehrlichiosis, products like Advantix or Seresto are often the preferred choice in these regions, as they help to repel ticks before they attach to your pet. Your local vet will have the best advice for your specific area.